Chaga is an exceptional medicinal mushroom with a wide range of special effects.
Chaga has a high melanin content which also gives it a characteristic coal-like appearance. Studies have shown that the melanin-complex contained in Chaga possesses high antioxidant properties and thus protects the genome Continue reading
The bioavailability of orally supplied glutathione (γ-Glutamylcysteinylglycine) could be proved.
Bioavailability Glutathione
The acetylating of vital nutrients may be a method to improve the bioavailability and stability of the substance.
I am critical about the administration of S-acetyl-glutathione or S-acetyl-L-glutathione because as far as I know there are no studies available which have examined the effects of this substance closely. A large number of studies exist about the proven efficacy of reduced glutahtione GSH. The acetylation may indeed increase the bioavailability, but also changes the molecule.
In any case, an influence of the body’s glutathione production (downregulation) due to oral administration of glutathione is not to be expected, since the production of glutathione depends on the presence of sulfur-containing amino acids and not on the glutathione level.
The bioavailability of orally administered glutathione could be verified in some studies. Most likely a part of the absorbed tripeptide glutathione is broken down by stomach acid into the individual amino acids. However, studies have verified that after oral supplementation of GSH (reduced glutathione) the blood levels of glutathione increase. (Refer to article: GSH blood levels increase after oral intake). After oral GSH application, blood levels increased, but only by GSH administration and not by intake of single amino acids components. This is an argument against the thesis explaining the increase in the blood concentration of glutathione only by the individual amino acids, which the body again must synthesize to glutathione. Glutathione may also be absorbed already in the mouth. See also article: Glutathione Absorption in the Gastrointestinal Tract
Thus, the oral ingestion of glutathione is advisable.
For the application of S-acetyl glutathione refer to S-Acetyl Glutathione versus GSH
Copyright © Dr. med. Alexander Michalzik
Without the “Antioxidant Network” the body cannot survive. Many diseases that occur more frequently in old age, such as cardiovascular disease, diabetes, eye and skin diseases, tumors, etc. are the result of oxidation processes of body tissues. Here L-glutathione (GSH) in its reduced form has a key position.
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For over 50 years the dogma exist that brain cells cannot regenerate. Considering the fact that every day many brain cells perish, this is not a pleasant idea. In 1998, the Swedish scientist Thomas Björk Eriksson of the University of Gothenburg verified the formation (regeneration) of new nerve cells in adults (hood) for the first time. Especially in the hippocampus (region) area, this effect could be demonstrated. Elizabeth Gould explored the influence of stress on the brain cells and the possible mechanisms for the formation of new cells. Continue reading